University of Dundee, UK | Postdoctoral Researcher – Mass Spectrometry & LRRK2 Signalling in Parkinson's Disease
Organization
University of Dundee
Duration
1 Year (Fixed-Term)
Fellowship Amount
Grade 7 Salary (£37,694–£46,049 per annum)
Overview
About the Position
The University of Dundee is recruiting an outstanding Postdoctoral Researcher to join the internationally renowned MRC Protein Phosphorylation and Ubiquitylation Unit (MRC PPU) within the Faculty of Life Sciences. The successful candidate will work on cutting-edge research investigating LRRK2 signalling in Parkinson's disease using advanced mass spectrometry and quantitative proteomics. DRA PDRA Job advert
The project is funded through the Michael J. Fox Foundation (MJFF) LRRK2 Investigative Therapeutic Exchange (LITE) Initiative, aiming to accelerate biomarker discovery and therapeutic development for Parkinson's disease. Researchers will collaborate with leading academic, clinical, and industry partners worldwide. DRA PDRA Job advert
Research Responsibilities
The selected researcher will:
- Conduct advanced mass spectrometry experiments on LRRK2 signalling.
- Investigate Rab GTPase phosphorylation and lysosomal signalling.
- Develop organelle proteomics workflows.
- Generate quantitative proteomics and phosphoproteomics datasets.
- Identify biomarkers for Parkinson's disease.
- Analyze large biological datasets using Python and R.
- Publish research in leading international journals.
- Mentor students and contribute to collaborative research activities. DRA PDRA Job advert
Research Environment
The researcher will gain access to one of the world's most advanced proteomics facilities equipped with:
- Orbitrap Astral
- Orbitrap Exploris 480
- Orbitrap Lumos
- timsTOF SCP systems
- Automated sample preparation platforms
The project also offers collaborations with Stanford University and the global LITE research network. DRA PDRA Job advert DRA PDRA Job advert
Eligibility Criteria
Applicants should possess:
- Ph.D. (completed or near completion) in a relevant discipline.
- Strong publication record.
- Experience in quantitative mass spectrometry.
- Knowledge of computational proteomics.
- Expertise in Python or R for data analysis.
- Experience with Orbitrap or timsTOF instrumentation is desirable.
- Interest in neurodegeneration, Parkinson's disease, or translational research is preferred. DRA PDRA Job advert
Benefits
The University offers:
- International research collaborations.
- Advanced scientific training.
- Independent research development opportunities.
- Relocation support.
- Family-care support through the LITE Care & Career Programme.
- Access to world-class proteomics infrastructure. DRA PDRA Job advert
About the University
The University of Dundee is internationally recognized for excellence in life sciences, biomedical research, and innovation. The institution provides an inclusive and diverse research environment with scientists from over 40 countries and strong support for professional development. DRA PDRA Job advert
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Financial Support
Fellowship Amount: Grade 7 Salary (£37,694–£46,049 per annum)
Eligibility Criteria
Streams
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